常用名 | PZ09 | CAS号 | 1132609-87-0 |
---|---|---|---|
价格 | ¥需询单/1g | 纯度 | 98.9% |
备货期 | 1天 | 库存 | 现货 |
产品详情(用途,包装等)
PZ09 (PKC-zeta inhibitor 9, PKC-ζ inhibitor PZ9) is a potent, isoform selective PKC-zeta (PKC-ζ) inhibitor with IC50 of 5.18 nM, displays excellent selectivity (>200-fold) over other PKC isoforms with exception of PKC-i (10-fold); also shows high selectivity for CDK-2 (>200-fold), as well as a broader range of other kinases (<50% inhibition at 10 uM); PZ09 is a small-molecule inhibitor, the first tool to successfully interrogate aPKC signaling in cells. |