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伊曲康唑差向异构体

更新时间:2022-07-21 14:26:40

常用名 伊曲康唑 CAS号 84625-61-6
价格 ¥需询单/10mg ¥需询单/25mg ¥需询单/50mg ¥需询单/100mg 纯度 99.9%
备货期 需询单 库存 现货
 产品详情(用途,包装等)
用途:
Itraconazole is a triazole antifungal agent.IC50 Value: N/ATarget: antifungalin vitro: Itraconazole is pharmacologically distinct from other azole antifungal agents in that it is the only inhibitor in this class that has been shown to inhibit both the hedgehog signaling pathway and angiogenesis[1, 2]. These distinct activities are unrelated to inhibition of the cytochrome P450 lanosterol 14 alpha-demethylase and the exact molecular targets responsible remain unidentified. Functionally, the antiangiogenic activity of itraconazole has been shown to be linked to inhibition of glycosylation, VEGFR2 phosphorylation and cholesterol biosynthesis pathways [2].Evidence suggests the structural determinants for inhibition of hedgehog signaling by itraconazole are recognizably different from those associated with antiangiogenic activity [3].in vivo: Nine volunteers were given either 200 mg itraconazole, or matched placebo orally once daily for 4 days. On day 4, itraconazole increased the area under the midazolam concentration-time curve from 10 to 15 times (p 物理化学性质:
CAS号:84625-61-6
常用中文名:伊曲康唑
常用英文名:Itraconazole
分子式:C35H38Cl2N8O4
分子量:705.633
密度:1.4±0.1 g/cm3
沸点:850.0±75.0 °C at 760 mmHg
熔点:166°C
闪点:467.9±37.1 °C
储存条件:2-8°C

供应商信息

深圳菲斯生物科技有限公司

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地区: 广东省 深圳市 龙岗区
联系人:王晓红
联系人电话:13380397412
邮件:2843428289@qq.com
网址:http://www.phystandard.com.cn/
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深圳菲斯生物科技有限公司成立于2012年,是一家基于化学和医药科技基础的高科技企业。公司致力于新药及仿制药注册申报用药物标准品、杂质对照品的生产、研发和销售,承接杂质对照品的定制服务、未知杂质分析、分离纯化服务,同时提供参比制剂一次性进口、化学试剂、实验室耗材等,是集研发、生产、销售为一体的医药科技企业。
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参考价格:¥141.6/5g
其他供应商价格:
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2018-03-23 伊曲康唑
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2022-12-01 伊曲康唑 Itraconazole
价格:¥需询单
2017-12-29 伊曲康唑
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2017-08-15 伊曲康唑
价格:¥需询单

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