常用名 | LFF-571 | CAS号 | 1160959-55-6 |
---|---|---|---|
价格 | $需询单/100mg $需询单/250mg $需询单/1g | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-lff-571.html |
产品详情(用途,包装等)
LFF571 is a semisynthetic thiopeptide and bactericidal antibiotic that interferes with bacterial protein synthesis by inhibition of elongation factor EF-Tu, LFF571 is potent in vitro activity against C.difficile strains with MIC90 of 0.25 ug/mL.LFF571 demonstrated activity against most other Gram-positive rods and cocci (MIC50/90, 0.125/0.25 μg/mL) except for bifidobacteria and some species of lactobacilli, showed reduced active activity against Gram-negative anaerobes with MICs for Bacteroides fragilis of 4 and 8 μg/mL.LFF571 inhibits exogenous protein synthesis elongation factor EF-Tu and interferes with the ability for EF-Tu to deliver aminoacylated tRNA to the ribosome. |