多佐胺
更新时间：2025-09-08 10:50:23
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| 常用名 | 多佐胺 | CAS号 | 120279-96-1 |
|---|---|---|---|
| 价格 | ￥6498.0/1g ￥需询单/1g ￥需询单/1g ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品网页 | http://www.aladdin-e.com/zh_cn/D349665.html | ||
| 产品详情（用途，包装等）
用途： Dorzolamide(L671152; MK507) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.Target: carbonic anhydrase (CA)Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour [1]. Glaucoma was induced in the right eye of adult Wistar rats by episcleral venous occlusion. One experimental group was administered dorzolamide 2%-timolol 0.5% combination eye drops, while the other experimental group was administered dorzolamide 2% eye drops. Control groups had surgery without drug administration. Drug application was initiated either 2 weeks before surgery (Group A), from the day of surgery (Group B), 2 weeks after surgery (Group C), or 4 weeks after surgery (Group D). RGCs were labeled by intratectal Fluorogold injections and counted from flat-mount preparations, and IOP was measured using Tonopen. Both dorzolamide-timolol combination and dorzolamide, when applied topically, significantly reduced IOP and improved RGC densities in experimental eyes when compared to control eyes. Earlier initiation, as well as longer duration of drug application, resulted in higher RGC densities [2].Clinical indications: Glaucoma; Ocular hypertensionFDA Approved Date: 1995Toxicity: Dizziness, headache, shortness of breath, slow heartbeat, severe asthma, cardiac arrest 物理化学性质： CAS号：120279-96-1 常用中文名：多佐胺 常用英文名：Dorzolamide 分子式：C10H16N2O4S3 分子量：324.44 密度：1.53 g/cm3 沸点：575.8ºC at 760 mmHg 熔点：N/A 闪点：302ºC 储存条件：room temp |
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- 产品名：多佐胺
- 价格： ￥6498.0/1g ￥需询单/1g ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$70/10mg