| 常用名 | 3,6-二氯苯并[b]噻吩-2-羧酸 | CAS号 | 34576-94-8 |
|---|---|---|---|
| 价格 | ¥650.0/100mg ¥1100.0/250mg ¥2200.0/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 3 |
| 产品网页 | https://www.dcchemicals.com/product_show-34576-94-8.html | ||
| 产品详情(用途,包装等)
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC)[1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM[2]. |