Bisdemethoxycurcumin
更新时间：2022-01-28 19:58:44
采购访问：41次
| 常用名 | 双去甲氧基姜黄素 | CAS号 | 33171-05-0 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Bisdemethoxycurcumin(Curcumin III; Didemethoxycurcumin) is a natural derivative of curcumin with anti-inflammatory and anti-cancer activities.IC50 value:Target: Anticancer natural compoundin vitro: BDMC-induced apoptosis was mediated by a combinatory inhibition of cytoprotective proteins, such as Bcl2 and heme oxygenase-1 and increased generation of reactive oxygen species. Intriguingly, BDMC-induced apoptosis was reversed with co-treatment of sr144528, a cannabinoid receptor (CBR) 2 antagonist, which was confirmed with genetic downregulation of the receptor using siCBR2 [1]. Induction of cell cycle arrest in HepG2 cells by NB and BDCur in combination was evidenced by accumulation of the G2/M cell population. Further investigation on the molecular mechanism showed that NB and BDCur in combination resulted in a significant decrease in the expression level of Cdc2 and cyclin B [2]. BDMC treatment activated Sirt1/AMPK signaling pathway. Moreover, downregulating Sirt1 by the pharmacological inhibitor nicotianamine or small interfering RNA blocked BDMC-mediated protection against t-BHP-mediated decrease in proliferation [4].in vivo: human gastric adenocarcinoma xenograft model was generated in vivo using nude mice and BDMC was observed to suppress the growth and activity of tumors, in addition to improving the physical and mental capacity of the mice [3]. 物理化学性质： CAS号：33171-05-0 常用中文名：双去甲氧基姜黄素 常用英文名：Bisdemethoxycurcumin 分子式：C19H16O4 分子量：308.328 密度：1.3±0.1 g/cm3 沸点：551.3±45.0 °C at 760 mmHg 熔点：221-223ºC 闪点：301.3±25.2 °C 储存条件：-20°C |
达阳化工（杭州）有限公司
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主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
主要合作伙伴：
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：双去甲氧基姜黄素
- 价格：
- 纯度：99.5%
- 备货期：10天
- 联系人：徐经理
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：双去甲氧基姜黄素
- 价格： ￥448.0/20mg
- 纯度：98.0%
- 备货期：2天
- 联系人：刘佳
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：双去甲氧基姜黄素
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：双去甲氧基姜黄素
- 价格： ￥984.9/25mg ￥308.9/5mg ￥2247.9/100mg ￥492.9/10mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥665/10mg