| 常用名 | Hydroxy desmethyl Bosentan | CAS号 | 253688-62-9 |
|---|---|---|---|
| 价格 | $需询单/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 3 |
| 产品网页 | https://www.dcchemicals.com/product_show-Hydroxy-desmethyl-Bosentan.html | ||
| 产品详情(用途,包装等)
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver. Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Bosentan can be used in treatment of pulmonary arterial hypertension. |