常用名 | ONO-7475 | CAS号 | 1646839-59-9 |
---|---|---|---|
价格 | $600.0/100mg $950.0/250mg $1900.0/1g | 纯度 | 98.0% |
备货期 | 1天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-ONO-7475.html |
产品详情(用途,包装等)
ONO-7475 is a potent, selective, and orally active novel Anexelekto/MER tyrosine kinase inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. ONO-7475 sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. ONO-7475 combines with Osimertinib (HY-15772) provides a bright promise for the study of EGFR-mutated non-small cell lung cancer (NSCLC). |