| 常用名 | 非氨酯 | CAS号 | 25451-15-4 |
|---|---|---|---|
| 价格 | ¥50000.0/10kg ¥15000.0/1kg ¥600.0/10g ¥需询单/1ton | 纯度 | 98.0% |
| 备货期 | 2天 | 库存 | 现货 |
| 产品网页 | http://www.cyhxkj.com/prodetail/188.aspx | ||
| 产品详情(用途,包装等)
用途: Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .Target: NMDA ReceptorFelbamate (marketed under the brand name Felbatol by MedPointe) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy.Felbamate has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit. Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptor of relevance of NMDA receptor blockade as a strategy for the treatment of human epilepsy has been questioned. Therefore, the importance of the effects of felbamate on NMDA receptors to its therapeutic action in epilepsy is uncertain. 物理化学性质: CAS号:25451-15-4 常用中文名:非氨酯 常用英文名:felbamate 分子式:C11H14N2O4 分子量:238.240 密度:1.3±0.1 g/cm3 沸点:511.9±50.0 °C at 760 mmHg 熔点:148-1500C 闪点:288.4±26.4 °C 储存条件:Store at RT |