盐酸乙胺丁醇
更新时间：2021-08-28 17:22:44
| 常用名 | 乙胺丁醇 | CAS号 | 74-55-5 |
|---|---|---|---|
| 价格 | ￥需询单/25kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.Target: AntibacterialEthambutol directly affects two polymers, arabinogalactan (AG) and lipoarabinomannan (LAM) in Mycobacterium smegmatis. In M. smegmatis, Ethambutol inhibits synthesis of arabinan completely and inhibits AG synthesis most likely as a consequence of this; more than 50% of the cell arabinan is released from the bacteria following Ethambutol treatment, whereas no galactan is released. Ethambutol main targets against embB gene product in M. avium. Ethambutol induces 60% changes in the embB gene in M. tuberculosis resistant mutants [1]. Ethambutol is effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. Nearly all strains of M. tuberculosis and M. kansasii as well as a number of strains of the M. aviumcomplex (MAC) are sensitive to Ethambutol. [1] Ethambutol is potency against M. tuberculosis (H37Rv) with MIC of 0.5 μg/mL in vitro [2]. Ethambutol is efficient on treatment of mycobacterial-infected macrophages. When M. tuberculosis infected macrophages are treated with 6 μg/mL Ethambutol, the log CFUs following treatment for 3 days is 4.17, while value in control group is 4.8. The MICs for M. avium (MTCC 1723) and M. smegmatis (MTCC 6) are 15 μg/mL and 0.18 μg/mL, respectively. Ethambutol is efficient in animal model. 100 mg/kg Ethambutol given orally 15 days post i.v. infection 1 ×/week for 5 weeks, induces a lower log CFU compared with untreatment (4.59 vs 5.07) [3]. 物理化学性质： CAS号：74-55-5 常用中文名：乙胺丁醇 常用英文名：Ethambutol 分子式：C10H24N2O2 分子量：204.310 密度：1.0±0.1 g/cm3 沸点：345.3±22.0 °C at 760 mmHg 熔点：199 - 204ºC 闪点：113.7±12.9 °C 储存条件：2-8℃ |
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：乙胺丁醇
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Ethambutol
- 价格： ￥479.0/1g ￥889.0/5g ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：乙胺丁醇
- 价格： ￥499.9/1g ￥199.9/250mg ￥1799.9/5g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$60/1g