盐酸乙胺丁醇
更新时间：2020-04-06 20:40:06
| 常用名 | 盐酸乙胺丁醇 | CAS号 | 1070-11-7 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/100g ￥需询单/100kg ￥需询单/1ton | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Ethambutol Dihydrochloride is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.Target: AntibacterialEthambutol directly affects two polymers, arabinogalactan (AG) and lipoarabinomannan (LAM) in Mycobacterium smegmatis. In M. smegmatis, Ethambutol inhibits synthesis of arabinan completely and inhibits AG synthesis most likely as a consequence of this; more than 50% of the cell arabinan is released from the bacteria following Ethambutol treatment, whereas no galactan is released. Ethambutol main targets against embB gene product in M. avium. Ethambutol induces 60% changes in the embB gene in M. tuberculosis resistant mutants [1]. Ethambutol is effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. Nearly all strains of M. tuberculosis and M. kansasii as well as a number of strains of the M. aviumcomplex (MAC) are sensitive to Ethambutol. [1] Ethambutol is potency against M. tuberculosis (H37Rv) with MIC of 0.5 μg/mL in vitro [2]. Ethambutol is efficient on treatment of mycobacterial-infected macrophages. When M. tuberculosis infected macrophages are treated with 6 μg/mL Ethambutol, the log CFUs following treatment for 3 days is 4.17, while value in control group is 4.8. The MICs for M. avium (MTCC 1723) and M. smegmatis (MTCC 6) are 15 μg/mL and 0.18 μg/mL, respectively. Ethambutol is efficient in animal model. 100 mg/kg Ethambutol given orally 15 days post i.v. infection 1 ×/week for 5 weeks, induces a lower log CFU compared with untreatment (4.59 vs 5.07) [3]. 物理化学性质： CAS号：1070-11-7 常用中文名：盐酸乙胺丁醇 常用英文名：Ethambutol dihydrochloride 分子式：C10H26Cl2N2O2 分子量：277.232 密度：N/A 沸点：345.3ºC at 760 mmHg 熔点：198-200°C 闪点：113.7ºC 储存条件：Refrigerator |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：乙胺丁醇二盐酸盐
- 价格： ￥561.9/100g ￥149.9/25g ￥40.9/5g ￥1033.9/1ml
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：盐酸乙胺丁醇
- 价格： ￥88.0/1g ￥248.0/5g
- 纯度：98.0%
- 备货期：3天
- 联系人：刘佳
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸乙胺丁醇
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
查看所有供应商和价格请点击：
参考价格：￥421.2/10g