Y-27632 dihydrochloride
更新时间：2024-09-11 15:56:57
| 常用名 | Y-27632 2HCl | CAS号 | 129830-38-2 |
|---|---|---|---|
| 价格 | ￥需询单/1g ￥需询单/5g ￥需询单/10g ￥需询单/50g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情（用途，包装等）
Product Name: Y-27632 dihydrochloride; Y-27632 2HCl CAS No.: 129830-38-2; 146986-50-7 Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride; 4-[(1R)-1-Aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide dihydrochloride; (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride; (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide Molecular Formula: C14H21N3O.2HCl Molecular Weight: 320.26 Appearance:White solid Purity(HPLC): >99% Biological Activity: Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase respectively. Also inhibits the protein kinase C-related protein kinase, PRK2 (IC50 = 600 nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells undergoing cryopreservation. Y-27632 is a cell-permeable, highly potent and selective inhibitor of Rho-associated, coiled-coil containing protein kinase (ROCK). Y-27632 inhibits both ROCKI (Ki = 220 nM) and ROCKII (Ki = 300 nM) by competing with ATP for binding to the catalytic site. Y-27632 is a biochemical tool used in the study of the rho-associated protein kinase (ROCK) signaling pathways. Y-27632 selectively inhibits p160ROCK. Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP. |
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：trans-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：化源网
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Y-27632 2HCL
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Y27632二盐酸盐
- 价格： ￥5280.0/100mg ￥750.0/10mg ￥31500.0/1g ￥需询单/1mg
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：Y-27632 dihydrochloride
- 价格： ￥811.9/100mg ￥179.9/10mg ￥489.9/50mg ￥102.9/5mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：27632 (hydrochloride)
- 价格： ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
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参考价格：$55/10mM*1mLinDMSO