异钩藤碱
更新时间：2024-09-14 11:31:44
| 常用名 | 异钩藤碱 | CAS号 | 6859-01-4 |
|---|---|---|---|
| 价格 | ￥需询单/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Isorhynchophylline (IRN), an alkaloid isolated from Uncaria rhynchophylla, possesses the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage.IC50 value:Target:In vitro: Isorhynchophylline concentration-dependently inhibited the platelet-derived growth factor (PDGF)-BB-induced proliferation of PASMCs. Fluorescence-activated cell-sorting analysis showed that isorhynchophylline caused G0/G1 phase cell cycle arrest [2]. Isorhynchophylline can significantly attenuate the cardiomyocyte hypertrophy induced by AngⅡ [3].In vivo: Isorhynchophylline significantly improved spatial learning and memory function in the D-gal-treated mice. Isorhynchophylline significantly increased the level of glutathione (GSH) and the activities of superoxide dismutase (SOD) and catalase (CAT), while decreased the level of malondialdehyde (MDA) in the brain tissues of the D-gal-treated mice [1]. Isorhynchophylline prevented monocrotaline induced pulmonary arterial hypertension in rats, as assessed by right ventricular (RV) pressure, the weight ratio of RV to (left ventricular+septum) and RV hypertrophy. Isorhynchophylline significantly attenuated the percentage of fully muscularized small arterioles, the medial wall thickness, and the expression of smooth muscle α-actin (α-SMA) and proliferating cell nuclear antigen (PCNA) [2]. 物理化学性质： CAS号：6859-01-4 常用中文名：异钩藤碱 常用英文名：Isorhyncophylline 分子式：C22H28N2O4 分子量：384.47 密度：1.4±0.1 g/cm3 沸点：447.6±25.0 °C at 760 mmHg 熔点：114ºC 闪点：224.5±23.2 °C 储存条件：室温 |
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：异钩藤碱
- 价格： ￥688.0/20mg
- 纯度：98.0%
- 备货期：1天
- 联系人：刘佳
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：异钩藤碱
- 价格： ￥411.9/10mg ￥541.9/20mg ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$191/10mM*1mLinDMSO