[(NHC) AuI]??Catalyzed Formation of Conjugated Enones and Enals: An Experimental and Computational Study

N Marion, P Carlqvist, R Gealageas…

文献索引：Marion, Nicolas; Carlqvist, Peter; Gealageas, Ronan; De Fremont, Pierre; Maseras, Feliu; Nolan, Steven P. Chemistry - A European Journal, 2007 , vol. 13, # 22 p. 6437 - 6451

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被引用次数: 147

摘要

Abstract The [(NHC) Au I]-catalyzed (NHC= N-heterocyclic carbene) formation of α, β- unsaturated carbonyl compounds (enones and enals) from propargylic acetates is described. The reactions occur at 60 C in 8 h in the presence of an equimolar mixture of [(NHC) AuCl] and AgSbF 6 and produce conjugated enones and enals in high yields. Optimization studies revealed that the reaction is sensitive to the solvent, the NHC, and, to ...