On the synthesis of naphthoquinonyl heterocyclic amino acids

PB Shrestha-Dawadi, S Bittner, M Fridkin…

文献索引：Shrestha-Dawadi, Prativa Bade; Bittner, Shmuel; Fridkin, Mati; Rahimipour, Shai Synthesis, 1996 , # 12 p. 1468 - 1472

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被引用次数: 15

摘要

The reaction of 2, 3-dichloro-1, 4-naphthoquinone with L-histidine and L-tryptophan was performed in methanol in the presence of one equivalent of KOH and afforded the monochloro quinonyl derivatives 3e and 3f. Similar reaction with tryptamine and 6- aminoindazole in meth-anol or ethanol, afforded the heterocyclic amino quinones 3g and 3h. It is known that one of the chlorine atoms of 2, 3-dichloro-1, 4-naphthoquinone can be ...