Alkyl and diethylaminoethyl esters of N-substituted aminoacylaminobenzoic acids

E Epstein, D Kaminsky

文献索引：Epstein; Kaminsky Journal of the American Chemical Society, 1957 , vol. 79, p. 5814,5816

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被引用次数: 5

摘要

At the turn of the century and prior to his discovery of procaine, Einhorn and his associates synthesized a group of alkylaminoacetylaminobenzoates. lJ The clinical use of one of these, methyl 5-diethyIaminoacet ylaminosalicylate (Nirvanine), was discontinued because of its irritating properties. Since then several investigators3-* have prepared substituted anilide anesthetics and found them too irritating for clinical use. In 1946, Lofgreng prepared w- ...