Manganese porphyrins as redox-coupled peroxynitrite reductases

J Lee, JA Hunt, JT Groves

文献索引：Lee, Jinbo; Hunt, Julianne A.; Groves, John T. Journal of the American Chemical Society, 1998 , vol. 120, # 24 p. 6053 - 6061

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被引用次数: 190

摘要

Superoxide (O2-) and peroxynitrite (ONOO-) have been implicated in many pathophysiological conditions. To develop novel catalysts that have both ONOO- decomposition and O2-dismutase activity, and to understand the mechanisms of these processes, we have explored the reactivity of 5, 10, 15, 20-tetrakis (N-methyl-4'-pyridyl) porphinatomanganese (III)[Mn (III) TMPyP] toward ONOO-and O2-. The reaction of Mn (III) ...