Improved microwave-mediated synthesis of 3-(3-aryl-1, 2, 4-oxadiazol-5-yl) propionic acids and their larvicidal and fungal growth inhibitory properties

…, VP Brustein, DMAF Navarro, FAB dos Santos…

文献索引：Neves Filho, Ricardo Antonio Wanderley; Da Silva, Cecilia Aguiar; Da Silva, Clecia Sipriano Borges; Brustein, Vanessa Passos; Navarro, Daniela Maria Do Amaral Ferraz; Dos Santos, Fabio Andre Brayner; Alves, Luiz Carlos; Cavalcanti, Marilia Gabriela Dos Santos; Srivastava, Rajendra Mohan; Carneiro-Da-Cunha, Maria Das Gracas Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 8 p. 819 - 825

全文：HTML全文

被引用次数: 29

摘要

The synthesis of 3-(3-aryl-1, 2, 4-oxadiazol-5-yl) propionic acids from arylamidoximes and succinic anhydride under focused microwave irradiation conditions is described. The new synthetic method furnished the desired products in 2—3 min and good yields. Furthermore, the previously complicated purification procedure has been simplified in a manner which is quick, eco-friendly and cost-effective. Larvicidal bioassay and fungal growth inhibitory ...