Synlett

Reductive monoalkylation of aromatic amines via amidine intermediates

J Zhang, HM Chang, RR Kane

文献索引：Zhang, Jianxing; Chang, Hui-Min; Kane, Robert R. Synlett, 2001 , # 5 p. 643 - 645

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被引用次数: 8

摘要

Abstract: The convenience and efficiency of using amidines as intermediates in the reductive monoalkylation of aromatic amines has been demonstrated. This monoalkylation can be performed as either a two-step synthesis or a one-pot procedure. Several examples are presented which clearly demonstrate the utility of this new method for the methylation or ethylation of aromatic amines, including unprotected nucleosides. Key words: amidine, ...