Abstract In the absence of any additional ligands, the efficient N-arylation of nitrogen- containing heterocycles with aryl iodides catalyzed by relative low catalyst amount of Cu (OAc) 2· H 2 O was developed. This simple catalytic system is involved in the C–N cross- coupling reaction and works for a variety of pyrazole, pyrrole, imidazole, triazole, indole, benzoimidazole, benzotriazole, carbazole, and anilines as well as aryl iodides with ...