Tetrahedron

Cu (OAc) 2· H 2 O-catalyzed N-arylation of nitrogen-containing heterocycles

ZL Xu, HX Li, ZG Ren, WY Du, WC Xu, JP Lang

Index: Xu, Zhong-Lin; Li, Hong-Xi; Ren, Zhi-Gang; Du, Wei-Yuan; Xu, Wei-Chang; Lang, Jian-Ping Tetrahedron, 2011 , vol. 67, # 29 p. 5282 - 5288

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Citation Number: 47

Abstract

Abstract In the absence of any additional ligands, the efficient N-arylation of nitrogen- containing heterocycles with aryl iodides catalyzed by relative low catalyst amount of Cu (OAc) 2· H 2 O was developed. This simple catalytic system is involved in the C–N cross- coupling reaction and works for a variety of pyrazole, pyrrole, imidazole, triazole, indole, benzoimidazole, benzotriazole, carbazole, and anilines as well as aryl iodides with ...