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Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays

NS Sipes, MT Martin, P Kothiya, DM Reif…

文献索引:Vilches-Herrera, Marcelo; Miranda-Sepulveda, Juan; Rebolledo-Fuentes, Marco; Fierro, Angelica; Luehr, Susan; Iturriaga-Vasquez, Patricio; Cassels, Bruce K.; Reyes-Parada, Miguel Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 6 p. 2452 - 2460

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被引用次数: 61

摘要

... newly added chemicals, selected based on factors such as production volume, potential for ... The Phase II chemical set includes phthalates, alternative plasticizers, antimicrobials, pesticides, food ... compounds, and 111 failed drugs donated by six major pharmaceutical companies. ...