Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays

NS Sipes, MT Martin, P Kothiya, DM Reif…

Index: Vilches-Herrera, Marcelo; Miranda-Sepulveda, Juan; Rebolledo-Fuentes, Marco; Fierro, Angelica; Luehr, Susan; Iturriaga-Vasquez, Patricio; Cassels, Bruce K.; Reyes-Parada, Miguel Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 6 p. 2452 - 2460

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Citation Number: 61

Abstract

... newly added chemicals, selected based on factors such as production volume, potential for ... The Phase II chemical set includes phthalates, alternative plasticizers, antimicrobials, pesticides, food ... compounds, and 111 failed drugs donated by six major pharmaceutical companies. ...