Tetrahedron letters

An efficient stereoselective synthesis of (E)-and (Z)-trisubstituted alkenes from unactivated Baylis–Hillman adducts using NaBH 4/CuCl 2· 2H 2 O

B Das, J Banerjee, A Majhi, G Mahender

文献索引：Das, Biswanath; Banerjee, Joydeep; Majhi, Anjoy; Mahender, Gurram Tetrahedron Letters, 2004 , vol. 45, # 50 p. 9225 - 9227

全文：HTML全文

被引用次数: 29

摘要

Trisubstituted alkene moieties have been widely observed in several natural bioactive compounds including different pheromones and antibiotics. 1 The biological properties of these alkenes are highly dependent on their isomeric purity. Various trisubstituted alkenes with defined stereochemistry have also been used as key intermediates for the synthesis of other stereospecific compounds. 2 Thus a limited number of methods have been developed for ...