前往化源商城

The effects of substituting tetrazole for carboxyl in two series of anti??inflammatory phenoxyacetic acids

…, M Horlington, JGB Howes, JM Scruton…

文献索引:Drain; Daly; Davy; Horlington; Howes; Scruton; Selway The Journal of pharmacy and pharmacology, 1970 , vol. 22, # 9 p. 684 - 693

全文:HTML全文

被引用次数: 12

摘要

Series of o-phenylcarbamoyl-and o-benzamido-phenoxymethyl tetrazoles and o- phenylcarbamoylphenoxyacetic acids have been synthesized. Anti-inflammatory activity was measured by the phenyl benzoquinone writhing test in mice and the rat foot carrageenan oedema test. Potency in the two o-benzamido substituted series could not be related with structure in a satisfactory manner. Introduction of substituents into the benzene rings of the ...

 相关合成线路

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%