Synthesis of aryl-hydrazones via ultrasound irradiation in aqueous medium

…, LCD Coelho, FD de Menezes, DJ Brondani

文献索引：Leite, Ana Cristina Lima; Moreira, Diogo Rodrigo de M.; Coelho, Lucas Cunha Duarte; de Menezes, Frederico Duarte; Brondani, Dalci Jose Tetrahedron Letters, 2008 , vol. 49, # 9 p. 1538 - 1541

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被引用次数: 31

摘要

The synthesis of aryl-hydrazones from aromatic aldehydes/ketones and hydrazides (semicarbazide, thiosemicarbazide and aminoguanidine) is described using aqueous medium (acid conditions) under ultrasound irradiation with short reaction times (20–30min), the reactions occurring at room temperature and giving rise to good to excellent yields of the products, along with the diastereoselectivities. The procedure is also simple and clean.