Synthesis, 3D??QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors

L López, J Selent, R Ortega, CF Masaguer…

文献索引：ChemMedChem, , vol. 5, # 8 p. 1300 - 1317

被引用次数: 19

摘要

... ChemMedChem, 5: 1300–1317. ... Volume: Issue: Page: ... distance of two groups of hydrogen bond donor (HBD) hotspots, one near the benzolactam carbonyl and the other in front of the pyridyl or pyrimidyl moiety present in fragment I of some compounds (eg, 5 c and 5 d; Figure 4 ...

~9%

1196-38-9

3,4-二氢异喹啉-1(2H)-酮

~85%

~75%

Examining the binding mechanism of 3, 4-dihydro-3-(2-oxo-2-p...

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[Sicker, D.; Rabe, A.; Zakrzewski, A.; Mann, G. Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 6 p. 1063 - 1070]

Microwave-assisted N-debenzylation of amides with triflic ac...

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