Tetrahedron letters

A mild and selective method for the N-Boc deprotection by sodium carbonate

S El Kazzouli, J Koubachi, S Berteina-Raboin…

文献索引：El Kazzouli, Said; Koubachi, Jamal; Berteina-Raboin, Sabine; Mouaddib, Abderrahim; Guillaumet, Gerald Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8575 - 8577

全文：HTML全文

被引用次数: 28

摘要

A cleavage of N-tert-butyloxycarbonyl protection by Na2CO3 is reported. The N-free products are obtained in excellent yields. The compatibility of the method with the presence of acidic or basic groups is demonstrated. The reactions were performed on indole, azaindole, indazole, pyrazole, indolinone, quinolinone, and oxazolone.