Design, synthesis, and biological testing of novel naphthoquinones as substrate-based inhibitors of the quinol/fumarate reductase from Wolinella succinogenes

…, JW Bats, CRD Lancaster, H Schwalbe

文献索引：Nasiri, Hamid Reza; Bolte, Michael; Schwalbe, Harald Heterocyclic Communications, 2006 , vol. 12, # 5 p. 319 - 322

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被引用次数: 13

摘要

Novel naphthoquinones were designed, synthesized, and tested as substrate-based inhibitors against the membrane-embedded protein quinol/fumarate reductase (QFR) from Wolinella succinogenes, a target closely related to QFRs from the human pathogens