Organic & biomolecular chemistry

Zinc mediated allylations of chlorosilanes promoted by ultrasound: Synthesis of novel constrained sila amino acids

R Ramesh, DS Reddy

文献索引：Ramesh, Remya; Reddy, D. Srinivasa Organic and Biomolecular Chemistry, 2014 , vol. 12, # 24 p. 4093 - 4097

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被引用次数: 6

摘要

A simple, fast and efficient method for allylation and propargylation of chlorosilanes through zinc mediation and ultrasound promotion is reported. As a direct application of the resulting bis-allylsilanes, three novel, constrained sila amino acids are prepared for the first time. The design and synthesis of the constrained sila analogue of GABA (γ-amino butyric acid) is a highlight of this work.