Inorganic Chemistry 2012-10-01

Kinetic inertness of the Mn2+ complexes formed with AAZTA and some open-chain EDTA derivatives.

Ferenc K Kálmán, Gyula Tircsó

文献索引：Inorg. Chem. 51(19) , 10065-7, (2012)

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摘要

The results of systematic equilibrium, kinetic, and relaxometric investigations carried out on the Mn(2+) complexes of open-chain and AAZTA ligands indicate that the [Mn(CDTA)](2-) complex has satisfactorily high kinetic inertness (t(1/2) = 12 h at pH = 7.4), which, in turn, may allow its use as a contrast agent in the field of magnetic resonance imaging (as a replacement for Gd(3+)-based agents).