Chemical Communications 2005-01-14

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.

Anca Dragulescu-Andrasi, Peng Zhou, Gaofei He, Danith H Ly

文献索引：Chem. Commun. (Camb.) (2) , 244-6, (2005)

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摘要

Guanidine-based peptide nucleic acid (GPNA) with a d-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.