Organic letters

Functionalization of Unprotected Uracil Derivatives Using the Halogen-Magnesium Exchange

F Kopp, P Knochel

文献索引：Organic Letters, , vol. 9, # 9 p. 1639 - 1641

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被引用次数: 39

摘要

... Volume: Page ... Organic Letters. ... 13 More efficiently, the reaction of 7b with benzyl bromide after transmetalation using CuI·2LiCl furnishes the uracil derivative 9 in 57% yield (Scheme 1). The resulting products 8 and 9 are precursors of HEPT (10) and Emivirine (11 ...