Molecular Diversity 2010-08-01

One-pot multicomponent synthesis of two novel thiolactone scaffolds.

B Beck, S Srivastava, K Khoury, E Herdtweck, Alexander Dömling

文献索引：Mol. Divers. 14(3) , 479-91, (2010)

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摘要

We designed two novel thiolactone scaffolds. Both scaffolds can be accessed by a convergent Ugi multicomponent reaction (MCR) and are, thus, amenable to library synthesis. Design, stereoselectivity, structures, full experimental details, and virtual libraries will be reported.