Journal of the American Chemical Society

The Use of Organolithium Compounds to Effect the Alkylation of 2-and 4-Picoline1

C Osuch, R Levine

文献索引：Osuch; Levine Journal of the American Chemical Society, 1956 , vol. 78, p. 1723

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被引用次数: 53

摘要

The alkali amide-effected alkylations of 2-and 4-picoline, which have been studied by Chichibabin and co-workers, have received much attention in recent years. 3 Although this method usually gives satisfactory yields of products, the required reaction times often are excessive. Because of our favorable result^^-^ on the acylations of the lithium derivatives of 2-picoline and related tar bases, prepared from the tar bases and phenyllithium, we have ...