Heterocycles

Regioselective synthesis of 4-alkylpyridines from pyridine and aldehydes via dipole reversal process of 1, 4-dihydropyridine phosphonate

PH Lee, K Lee, JH Shim, SG Lee, S Kim

文献索引：Lee, Phil Ho; Lee, Kooyeon; Shim, Jun Hwan; Lee, Seong Guk; Kim, Sundae Heterocycles, 2006 , vol. 67, # 2 p. 777 - 784

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被引用次数: 6

摘要

Résumé/Abstract 4-Alkylation of pyridine has been accomplished by the reaction of ylides, derivated from 1, 4-dihydropyridine phosphonate via phosphonioalkoxy-carbonylation of pyridine with aldehydes and subsequent elimination of diisopropyl phosphate followed by aromatization with potassium tert-butoxide.