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Urethane protected amino acid N-carboxyanhydrides and their use in peptide synthesis

…, M Shabankareh, RK Blair, M Goodman…

文献索引:Fuller; Cohen; Shabankareh; Blair; Goodman; Naider Journal of the American Chemical Society, 1990 , vol. 112, # 20 p. 7414 - 7416

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被引用次数: 106

摘要

polystyrene resin'by being shaken for 45 min in toluene in the presence of 0.02 equiv of N- methylmorpholine, Fmoc-Leu-O-resin with a substitution of 0.4 meq/g was obtained after filtration, washing, and drying under high vacuum. The absence of racemization was established by standard solid-phase procedures.*