Cell Metabolism 2013-10-01

What's the Mtrr with your grandparents?

Eric L Greer, Yang Shi

文献索引：Cell Metab. 18(4) , 457-9, (2013)

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摘要

Reduced folate levels can cause developmental defects and megaloblastic anemia. Padmanabhan et al. (2013) show that mutation in mice of a folate metabolism gene, Mtrr, which encodes for methionine synthase reductase, causes developmental defects not only in the mutant progeny, but also in genetically wild-type descendants for up to four generations. Copyright © 2013 Elsevier Inc. All rights reserved.