Reduction of azides with zinc borohydride

BC Ranu, A Sarkar, R Chakraborty

文献索引：Ranu, Brindaban C.; Sarkar, Arunkanti; Chakraborty, Rupak Journal of Organic Chemistry, 1994 , vol. 59, # 15 p. 4114 - 4116

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被引用次数: 75

摘要

Zinc borohydride in 1, 2-dimethoxyethane provides an efficient procedure for the reduction of organic azides. Aroyl, acyl, and arylsulfonyl azides readily undergo reduction at room temperature to produce amides and sulfonamides in excellent yields; however, substitution with electronwithdrawing groups in the aroyl azides leads to the corresponding benzyl alcohols. Reduction of aryl and alkyl azides has also been achieved in high yields, under ...