Chemistry: A European Journal 2010-12-03

Integrated palladium-catalyzed arylation of heavier Group 14 hydrides.

Aldes Lesbani, Hitoshi Kondo, Yusuke Yabusaki, Misaki Nakai, Yoshinori Yamanoi, Hiroshi Nishihara

文献索引：Chemistry 16(45) , 13519-27, (2010)

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摘要

A convenient procedure has been developed for the preparation of Group 14 compounds by integrated palladium-catalyzed cross-coupling of aromatic iodides with the corresponding Group 14 hydrides in the presence of a base. The reaction conditions can be applied to the cross-coupling of tertiary, secondary, and primary Group 14 compounds. In most cases, the desired arylated products were obtained in synthetically useful yields. Even in the case of aryl iodides containing OH, NH(2), CN, or CO(2)R groups, the reactions proceeded with good to high yields with tolerance of these reactive functional groups. A possible application of this method is the unique synthesis of a fungicidal diarylmethyl(1H-1,2,4-triazol-1-ylmethyl)silane derivative.