Synthesis of 2-Aminoindole-3-carboxylic Acid Derivatives by the Copper (I) Iodide Catalyzed Reaction of N-(2-Iodophenyl) formamides with Malononitrile or …
Abstract An efficient method for the synthesis of 2-aminoindole-3-carbonitriles and 2- aminoindole-3-carboxylates by the reaction of N-(2-iodophenyl) formamides with malononitrile and cyanoacetates, respectively, in the presence of a catalytic amount of copper (I) iodide using potassium carbonate as a base is reported.
