Sugar-nucleotides such as GDP-mannose, GDP-fucose and UDP-glucose are important biomolecules with a central role in carbohydrate and glycoconjugate biosynthesis, metabolism and cell signalling. Analogues and mimics of naturally occurring sugar- nucleotides are sought after as chemical tools and inhibitor candidates for sugar-nucleotide- dependent enzymes including glycosyltransferases. Many sugar-nucleotides bind to their ...
