Discovery of 1-Methyl-1 H-imidazole Derivatives as Potent Jak2 Inhibitors

Q Su, S Ioannidis, C Chuaqui, L Almeida…

文献索引：Journal of Medicinal Chemistry, , vol. 57, # 1 p. 144 - 158

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被引用次数: 22

摘要

... Journal of Medicinal Chemistry. ... event in all patients with MPNs, comprising essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF).(5) MF is associated with the lowest survival rate among MPNs and represents a significant unmet medical need.(6 ...