Indanylidenes. 1. Design and synthesis of (E)-2-(4, 6-difluoro-1-indanylidene) acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and …

DL Musso, FR Cochran, JL Kelley…

文献索引：Journal of Medicinal Chemistry, , vol. 46, # 3 p. 399 - 408

全文：HTML全文

被引用次数: 52

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The (E)-indanylidenes (see Table 1) were prepared by several methods. The most often used method was method A, as depicted in Scheme 1. The key intermediate in this method is the appropriately substituted indanone. ...