Copper??Catalyzed Trifluoromethylation and Cyclization of Aromatic??Sulfonyl??Group??Tethered Alkenes for the Construction of 1, 2??Benzothiazinane Dioxide Type …

X Dong, R Sang, Q Wang, XY Tang…

文献索引：Dong, Xiang; Sang, Rui; Wang, Qiang; Tang, Xiang-Ying; Shi, Min Chemistry - A European Journal, 2013 , vol. 19, # 50 p. 16910 - 16915

全文：HTML全文

被引用次数: 28

摘要

1, 2-Benzothiazinane dioxides have been realized as a key structure in a large number of pharmaceutical active compounds, such as calpain 1 inhibitor, piroxicam, meloxicam, brinzolamide, and so forth.(Figure1).[1] Medical applications of this type of compound are not only restricted in antibiosis and antidiabetic, but also as diuretics, and antithyroid and antitumor drugs.[2] Nowadays, in order to satisfy the need of a daily expanding global ...