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Purines. VIII. The Aminolysis of Certain Chlorosubstituted Purines1

SR Breshears, SS Wang, SG Bechtolt…

文献索引:Breshears et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 3789,3790

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被引用次数: 23

摘要

2, 6-Dichloropurine and 2, 6, 8-trichloropurine were treated with a number of nitrogenous bases. The reactions were found to be stepwise with the 6-position being preferentially aminated. In the case of very active aminating agents the stepwise reaction was accomplished by using aqueous solutions of the amine. For complete aminolysis of the less reactive amines it was necessary to employ pressure equipment. The proof of structure of ...

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