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Beilstein Journal of Organic Chemistry 2012-01-01

Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization.

Chunhui Dai, Bo Liang, Corey R J Stephenson

文献索引:Beilstein J. Org. Chem. 8 , 986-93, (2012)

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摘要

A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields. Further exploration of the molecular diversity of these compounds is demonstrated through Diels-Alder reactions.

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结构式 名称/CAS号 全部文献
5-苯基-1,3-环己二酮 结构式 5-苯基-1,3-环己二酮
CAS:493-72-1