Beilstein Journal of Organic Chemistry 2012-01-01

Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization.

Chunhui Dai, Bo Liang, Corey R J Stephenson

Index: Beilstein J. Org. Chem. 8 , 986-93, (2012)

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Abstract

A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields. Further exploration of the molecular diversity of these compounds is demonstrated through Diels-Alder reactions.

Structure	Name/CAS No.	Molecular Formula	Articles
	5-Phenylcyclohexane-1,3-dione CAS:493-72-1	C₁₂H₁₂O₂

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Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization.

Abstract

Related Compounds