Synlett

Lewis Acid-Catalyzed Reductive Amination of Carbonyl Compounds with Aminohydrosilanes

K Miura, K Ootsuka, S Suda, H Nishikori, A Hosomi

文献索引：Miura; Ootsuka; Suda; Nishikori; Hosomi Synlett, 2001 , # 10 p. 1617 - 1619

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被引用次数: 16

摘要

Abstract: The TiCl4-catalyzed reaction of aromatic carbonyl compounds with (dialkylamino) dimethylsilanes gave tertiary amines in moderate to high yields. The reductive amination of aliphatic aldehydes was effectively catalyzed by ZnI2. Methyl N-(dimethylsilyl) carbamate as well could be used for reductive amination of carbonyl compounds in the presence of Ph3CClO4. Key words: Lewis acids, reductive aminations, amines, aldehydes, ...