Journal of the American Chemical Society

Chemical model studies for the mechanism of vitamin K epoxide reductase

RB Silverman

文献索引：Silverman Journal of the American Chemical Society, 1981 , vol. 103, # 19 p. 5939 - 5941

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被引用次数: 72

摘要

11 9 spectra, and IR" spectrum. The stereochemistry drawn for 8 was derived from the known reaction of thiols with epoxides to yield exclusive anti-@-hydroxy sulfides14 (and from the isolation of the same compound with base catalysis as described below). When the reaction was allowed to proceed for 6 h, a 52% yield of 8 and a 40% yield of 2, 3-dimethyl-1, 4-naphthoquinone (9), identified by comparison of its NMR and IR spectra with those of an ...